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原标题：天气和气候变化对室内外空气质量的改变对哮喘患者的影响（AAAAI 工作报告 ）
　　天气和气候变化是一个持续变化的过程，影响过敏和哮喘。本报告旨在提供自上次气候变化审查以来的信息，重点关注哮喘疾病。PubMed和互联网搜索主题包括气候和天气变化、空气污染、颗粒物、温室气体、交通、昆虫栖息地和症状缓解，以及作者个人提供的参考资料。气温升高和大气中二氧化碳含量增加引起的室外空气过敏原模式变化是导致花粉季节持续时间延长、花粉产量增加和花粉过敏性可能增加的主要因素。预计气候变化对室内空气污染的威胁包括洪水引发的微生物和霉菌生长，人员流离失所以及暴露工人呼吸保护的需要。室内燃烧驱蚊剂造成的空气污染是昆虫栖息地区域增加的潜在预期结果。化石燃料燃烧产生的空气污染和与交通有关的排放会改变呼吸防御机制，并与特定的过敏原协同作用，增强免疫原性，使易感受试者的哮喘恶化。社区环保的努力可以显著减少空气污染，从而减少温室气体排放，改善空气质量。过敏症专家应对天气模式变化的方法应该是综合的，并且是预期的，以保护高危患者。


延伸阅读
JACI
Impact of weather and climate change with indoor and outdoor air quality in asthmatic patients  
DOI: org/10.1016/j.jaci.2019.02.018
Abstract: 
Weather and climate change are constant and ever-changing processes that affect allergy and asthma. The purpose of this report is to provide information since the last climate change review with a focus on asthmatic disease. PubMed and Internet searches for topics included climate and weather change, air pollution, particulates, greenhouse gasses, traffic, insect habitat, and mitigation in addition to references contributed by the individual authors. Changes in patterns of outdoor aeroallergens caused by increasing temperatures and amounts of carbon dioxide in the atmosphere are major factors linked to increased duration of pollen seasons, increased pollen production, and possibly increased allergenicity of pollen. Indoor air pollution threats anticipated from climate changes include microbial and mold growth secondary to flooding, resulting in displacement of persons and need for respiratory protection of exposed workers. Air pollution from indoor burning of mosquito repellants is a potential anticipatory result of an increase in habitat regions. Air pollution from fossil fuel burning and traffic-related emissions can alter respiratory defense mechanisms and work synergistically with specific allergens to enhance immunogenicity to worsen asthma in susceptible subjects. Community efforts can significantly reduce air pollution, thereby reducing greenhouse gas emission and improving air quality. The allergist's approach to weather pattern changes should be integrated and anticipatory to protect at-risk patients.
First Author:
Jill A. Poole  
Correspondence:
Nebraska Medical Center, Omaha, NE 68198.
All Authors:
Jill A. Poole, Charles S. Barnes, Jeffrey G. Demain, Jonathan A. Bernstein, Mahesh A. Padukudru,  William J. Sheehan, Guillermo Guidos Fogelbach, James Wedner, Rosa Codina, Estelle Levetin, John R. Cohn, Steve Kagen, Jay M. Portnoy, Andre E.
　　创建过敏性疾病的科研、科普知识交流平台，为过敏患者提供专业诊断、治疗、预防的共享平台。